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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

移动端取代网页端。
The captain must steer the ship. If leadership doesn’t know where a project or company is headed, how can the company know? This isn’t just about steps or deliverables, either, but a clear vision of the department or company’s future that he or she can communicate to the employees。

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

因为这里说的是BBC的夏洛克,所以你的华生不是真傻,只是用自己的方式展现智慧。他还有点不确定自己的性向(万一是直的呢)。
厌倦了一成不变的生活?何不去探险,让身心重新焕发活力?毫无疑问,南极洲会是个好去处。亲眼目睹企鹅嬉戏,成群结队的海鸟飞过天空,要比观看电视纪录片更令人兴奋。想象一下,置身于雄伟冰山和原生态山脉构成的世界中,是多么刺激和美好的一件事啊!但要注意的是,南极洲地处极地,因此行前要做好充足准备。保暖靴、防寒外套、手套、羊毛袜和帽子一样都不能少。

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

From the themed collection: 材质 功能设计决定卫浴产品价格
Open Access Perspective

Soft matter science and the COVID-19 pandemic

n. 珠宝,珠宝类

Graphical abstract: Soft matter science and the COVID-19 pandemic
From the themed collection: 房山红色旅游助推乡村发展
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

The runner-up was Lucy Kay, with Bars and Melody in third place.

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

-
单词entertainment 联想记忆:
Participants in the study were between the ages of 18 and 44 and were asked to run twice – with and without shoes. After completing their quick runs, researchers found that the heart rate and overall run speed of each participant had no effect on memory, but the presence of shoes or bare feet did. The researchers have hypothesized that the need to engage the mind while running barefoot to avoid pebbles or other impediments could have a positive impact on a person's ability to remember things. If you're an adventurous person, you might try taking a barefoot jog around the block before your next test or before you need to remember something important.
Hilcorp Energy:能源公司的个性化奖励

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

In one tweet that was posted on Jan 10, Obama wrote, "Thank you for everything. My last ask is the same as my first. I'm asking you to believe - not in my ability to create change, but in yours."
财新经济学家何帆表示:“这表明宏观经济已进一步趋稳,经济结构正在改善。今后必须协调财政政策和货币政策,尽可能避免大规模刺激。”
?The Aston Martin doesn't hurt. Not at all. Neither does dropping tons of cash at exotic casinos -- throwing money around makes men more attractive to women who are interested in flings. And, like Bond, men who gamble with women around are better at it.
单词discourse 联想记忆:

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

《Trigger Mortis》于9月8日发行,先于10月26日上映的007新电影《(幽灵党(暂译)》(Spectre)。

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
From the themed collection: 信托业加速转型服务实体经济
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

Coca-Cola cut its sales forecast for this year as it struggles with a consumer slowdown in China, sending the drinks group’s shares down more than 3 per cent.

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

The show airs on CBS December 4.
目前我在创业领域中所关注的大趋势之一是“接触或获得的权利”。创新者们正在将曾经昂贵的、耗时的,或是不可能获得或效率极低的产品带给消费者。无论是学习新技能、激发新兴趣,亦或是叩开此前成本高昂的市场,创业家们正在寻找全新的方式来将独一无二且术业专攻的产品带向更为主流的市场。我们开始看到合作消费商业模式中出现了这个趋势,而我预测,我们将在未来几年看到“基于接触或获得的权利”商业模式的潮涌。

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

The maker of Post-it notes and Scotch tape authorized a $12 billion stock repurchase program in February, replacing its current $7.5 buyback program. 3M's (MMM, Fortune 500) move followed its announcement late last year that it intends to spend $10 billion on acquisitions and repurchase up to $22 billion of shares over the next four years.
然而据北京出入境边防检查总站(Beijing General Station of Exit and Entry Frontier Inspection)称,只有14,000名旅客办理了过境免签手续,远低于官方此前预计的20,000人。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

Lady Gaga以5.9千万位列第四,其后是5.45千万的碧昂斯。前者在统计期间演出了66场,也靠与范思哲和MAC的合约获得收入,同时还有她自己的黑色香水。后者与其老公Jay Z的On The Run巡回演唱会通过19天(北美日期),赚得了超过10千万,创造了能与滚石相比较的第一对音乐界夫妻档夜平均的神话。
注册人数:424人

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

埃玛·莫拉诺一生中唯一的成就可能就是坚持。她活了117岁,并把自己的长寿归功于生鸡蛋和没有丈夫。她于4月15日去世。
embrace
最佳迷你剧集/电影类编剧:D?V?蒂文森斯(D.V. DeVincentis),《美国罪案故事:公诉辛普森》,“玛西亚,玛西亚,玛西亚” (The People v. O. J. Simpson: American Crime Story, "Marcia, Marcia, Marcia")
但是这位少年依然没有放弃,他还留了最后一手。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

This groundbreaking fight is loosely based on a bout between Chuck Wepner and Muhammad Ali, in which the "everyman" Wepner managed to become one of the four men to knock Ali down in his career. Just like in the film, Wepner pushed Ali through 15 rounds despite looking (and feeling) like he'd been hit by a truck. While both he and Rocky ended up losing their fights on a technicality, Wepner wins in our book for inspiring such an awesome character.

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

这位设计师晚年最重要的伙伴之一就是他的伯曼猫邱佩特,拉格菲尔德称它为他唯一的真爱,而且他还曾说过,如果(与动物结婚)合法的话,他会与邱佩特结婚。
前述北京微信用户Robin Wang说,11年前他是一位忠实的QQ用户,但现在已经停用这款即时通讯服务,因为它显得不够专业。但自从在手机上下载微信之后,他发现多数同事和朋友都在上面,现在大家都通过语音邮件交流了。

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

单词association 联想记忆:

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

除了要符合质量标准之外,进口商品还必须按中国规定正确标注。

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

该报道表示:“乐天将伤害中国人民,后果可能是严重的。”该报道发表之后,中国政府对乐天在中国的商业集团开展了多起调查。
傲人的财务业绩和令人炫目的新科技,或许已足以让这位钢铁般坚定的苹果首席执行官赢得英国《金融时报》2014年年度人物(Person of the Year)的称号。但库克阐述自己价值观的勇气,同样让他与众不同。
根据中国海关总署(General Administration of Customs)的数据,在经历了此前一个月的同比下跌1.4%之后,11月份中国的进口同比增长6.7%,至1522亿美元,远高于同比收缩1.9%的预测中值。
莱斯特大学研究人员表示,这副骸骨的DNA同理查三世一名姐妹的后代吻合,而且骸骨的脊柱弯曲,有战争留下的创伤,这都与历史记载吻合。

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

一个问题接着一个问题,从伊朗制裁到从阿富汗撤军,他的位置和政府态度之间的差别不大,但罗姆尼坚持他将更有效地加强美国的力量。
3. 向他人学习。
1.世界杯赛期间的一整个月电视遥控器都由我控制。
谷歌公司一名发言人在上周三时表示,该公司意识到“这是一个错误,哈维尔是无心之失”。
The show started with a circus theme, complete with acrobats, a sword-swallower and a man on stilts. Justin Bieber, Rihanna and Bruno Mars performed.

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
From the themed collection: “以房养老”还需精细制度设计
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

然而,北方高等商学院毕业生的国际化流动程度最高,2014届毕业生有85%曾在国外工作。
尽管这笔节省下来的钱目前看来相当可观,但其实远不够填补随之而来的不断升高的患病率所增加的社会负担的窟窿。

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

扎实推进“一带一路”建设。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

Mr Li said the economy’s strength came as a result of the government shunning strong stimulus policies and its push for supply-side reforms.

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

As for Dirk, nobody should ever go out the way they do, but it happens all the time. In some ways, maybe it's easier if the reckoning is this painful.
That put outbound investment for October at $8.3bn, according to FT calculations based on official data, for a year-on-year fall of 26.5 per cent.
'It's all bullshit. It's a lie. It's a Band-Aid lie to make them feel better. I know these people, I know they're lily-livered, and as long as it looks good on the surface, to them, that's enough.'
《剧集人生》(Episodes):映时频道的这部喜剧经常被忽视,它讲述的是两位被困在好莱坞的英国电视编剧在为马特·勒布朗(Matt LeBlanc)创作电视剧时遇到的困惑。勒布朗在剧中饰演他自己,演得很精彩。以娱乐业为背景的电视剧很少能保持最初的巧妙构思,但这部剧的第三季比前两季还要精彩。

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
From the themed collection: 建材市场下半年或迎第二春?
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

According to China's business magazine New Fortune's 2018 Chinese wealthy list, the top 10 tycoons' total wealth reached 1.72 trillion yuan, accounting for 18% of the combined wealth of the list's total 500, and the top 10's personal wealth has surpassed 100 billion yuan for the first time.
虽然考辛斯喜怒无常的性格和高使用率确实是个麻烦,但是仍然有很多理由做出这个交易:
3.Artificial Pancreas
China’s handling of its state reserves of raw materials such as cotton and sugar will be a key factor shaping the direction of agricultural commodities in 2017, according to a major lender to agribusinesses.

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

会。在2018年美联储可能多次加息的情况下,新兴市场中的交易可能会波动起伏。有时可能感觉有点像2013年“削减恐慌”(taper tantrum)重演。然而,平均GDP增速将升至5%,高于去年4.7%的预测值。这主要是因为近来处境艰难的俄罗斯和巴西境况将好转。
事实上,去往俄罗斯有许多可供选择的廉价航班。其国内的西伯利亚大铁路也使得交通十分便利。

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

The same seven schools continue to dominate the top half of the ranking. AGSM at UNSW Business School of Australia entered the ranking for the first time in eighth position.
卡戴珊,这就是女子精修学校入门级的简单礼仪:并拢双膝和脚踝,然后侧身就可以了。
我冒死地想一想,湖人队在几周后会不会也加入这一阵列呢?照目前这情况,他们必须打出史诗级别烂地比赛才能留住他们的选秀权(给费城的前三保护签位),问题取决于他们是会围绕现有阵容继续缓慢地重建呢还是为了得到下一个巨星扔掉一两个年轻球员呢。
“It’s horrible,” he said. “Whenever I see someone with a gun, I take it away and report it to police.”
adj. 特指的;指定的

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

China has ample foreign exchange reserves to satisfy the demands of imports and short-term debt repayments.
我们准备今年在香港和内地试行“债券通”,也就是说允许境外资金在境外购买内地的债券,这是第一次。香港是近水楼台先得月。
这部电影有实力冲击很多奖项,但很难领跑其中的任何一项。也许“甜茶”蒂莫西?柴勒梅德的表演是该片冲奥的最大可能。

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

二、2017年工作总体部署
1. Am I taking care of myself? Sometimes we get so wrapped up in taking care of others that we forget to take care of ourselves. It can be so easy to leave ourselves behind.

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
From the themed collection: 装修刚过半 工程意外停工
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

For all of these films, Ms. Swinton used the same tooth-designing specialist, Chris Lyons of the company Fangs F/X in London. His work has led him to designing all manner of teeth, including gold fangs fitted for a Doberman used in a Kanye West music video.
法国巴黎高等商学院排名第二,尽管该学院在除MBA以外的所有排名中都胜过伦敦商学院。法国巴黎高等商学院最终不敌伦敦商学院的原因是,其高管MBA课程Trium是与伦敦经济学院(London School of Economics)和纽约斯特恩商学院(Stern School of Business)合办的,因此这门课程在该项排名中的得分只有总得分的三分之一。(合办课程的商学院参与EMBA课程排名时按比例获得分值。)
Emma Morano’s singular achievement in life may have been perseverance. She lived for 117 years, crediting her longevity to raw eggs and her lack of a husband. She died on April 15.

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

《小镇疑云》,BBC America,3月4日播出。大卫·田纳特(David Tennant)携第二季归来,在这部引人共鸣的英国推理剧中继续饰演亚力克·哈迪(Alec Hardy)探员(去年他在美国翻拍版的《小镇疑云》[Gracepoint]中饰演埃米特·卡弗探员)。这部剧将于周一在英国首映,制作人们已经开始谈起第二季的秘密情节了,编剧克里斯·齐布纳尔(Chris Chibnall)在接受英国杂志采访时说的话可能会让剧迷不爱听,“第二季不是讲罪案的。”奥莉薇娅·科尔曼(Olivia Colman)继续饰演艾丽·米勒(Ellie Miller)探员,夏洛特·兰普林(Charlotte Rampling)和玛丽安娜·琼-巴普迪斯特(Marianne Jean-Baptiste)也加入了演员阵容。
scary puppy like head tilts and glares
Chinese billionaire Wang Jianlin, whose company owns AMC Theaters climbed into the top 20.

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
From the themed collection: 甲醛影响租客对长租公寓的信任
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

她说,在人民币升值的同时,与中国在旅游业方面构成竞争关系的国家(如日本)的货币贬值,这意味着到其他一些亚洲国家旅游的费用更加便宜,而来中国旅游更贵了。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
From the themed collection: 百安居让人不心安
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

“An employee packed up her belongings and walked out without a word.”

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

当年秋天开学后,达洛伊西奥开始感觉到肩上背负起了来自投资方的巨大压力。他需要改善软件的运算法则,于是他找到了以色列一个从事自然语言处理的编程团队,并签订了合同。他还用谷歌(Google)搜索找到了一位居住在泰国、在该领域有过重要著作的退休教授。达洛伊西奥说,他成了我们的科研主管,他现在在雅虎的森尼维尔办公室工作。
根据弗雷斯特研究公司(Forrester Research)的预测,今年美国网络商店的销售额将达到2,940亿美元,约为全国零售总额的9%。据弗雷斯特预计,到2018年,电子商务将占到全美零售总额的11%,约4,140亿美元,其中通过平板电脑和智能手机进行的交易约占线上销售额的20%。

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

SplashData发布这份榜单是为了鼓励大家使用复杂的密码。摩根·斯兰还说道:“和往常一样,我们还是希望通过了解使用简单密码存在很大风险,大家能设立比较严谨的密码来保护自己,并在不同的网站上使用不同的密码。”
4.Venice, Italy
对于购房者,也不都是坏消息:房价明年(2015年——译注)仍将上涨,但步伐可能会从飙涨趋于平缓。“房价不会一味地陡然上涨,”柯克兰集团(Corcoran)的首席执行官帕梅拉·利伯曼(Pamela Liebman)说,“买家都有点疲劳了。”
The survey is based on costs of over 160 items ranging from food and clothing, to domestic help, transport and utilities.

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

as朝向,soci(同伴,社会)-成为同伴-联合
因此,39%的90后试图避免使用手机所带来的负面影响,措施包括关闭APP的消息提示功能、限制社交媒体互动频率、以及在某些情况下完全不使用社交媒体等等。

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
From the themed collection: 中介须尽职 谨防买卖双方有纠纷
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

One of the main strengths of the LBS programmes is the wide range of students from different countries. More than 90 per cent in its 2015 MBA cohort were from overseas, coming from about 60 different countries.
伦敦商学院的学员品质优秀,这让该商学院尤其具有价值。一位2011届的MBA学员表示:“跻身于如此人才济济的学习环境让我坚信,我可以独立做成某些事情。”

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

9.The Bling Ring

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

In an explanation released alongside the latest data, the statistics bureau credited ongoing growth in producer prices in part to coal extraction and washing prices, up 15.4 per cent for the period and accelerating 11.3 percentage points from a month earlier.
Two days ago here in Brazil, we were shocked when we spent some time with some children living on the streets. And this is what one child told us: "I wish I was rich and if I were, I would give all the street children food, clothes, medicine, shelter and love and affection." 在巴西,我被2天前见到的情景震惊了,那时我和当地的小孩在玩耍,其中一个小孩说:“我希望我能富裕起来,然后我会给这个街道所有的小孩饭吃,给他们衣服穿,医疗,住房和爱”。
St Gallen outperforms other ranked schools thanks in part to strong scores for international criteria. More than 90 per cent of students and 80 per cent of faculty are from abroad. The school is also ranked second for both the international mobility of its students and their international exposure during the programme.
You see all kinds of grisly, hairy characters on the Tube but few commuters would've expected to see a pack of pandas on the platform.

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

In dollar terms, imports plunged 18.8 per cent last month to $114.19, from a 7.6 per cent drop in January and versus an expected drop of 3.6 per cent.
2010 U.S. unemployment rate (average): 10.2%

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

超过了9月份11.2%的上涨幅度。
但是,如果《广告狂人》向我们展示了什么的话(除了修身西服看起来多酷,宽领带真的不是男装的点睛之笔),那么,它最主要展示的是,60年代非常复杂,往往不太愉快,偶尔具有破坏性。
两岸是骨肉同胞,血浓于水,不管岛内形势如何变化,都割断不了两岸的亲情,也改变不了我们维护两岸关系和平发展的决心和诚意。

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

5.3-D 打印耳朵
Sweden, one of the most generous countries in terms of contributing funds to humanitarian aid, ranks No. 6 overall. The country is No. 2 in Citizenship and No. 1 in Best Countries for Green Living.
单词turkey 联想记忆:

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

中国官方PMI指数从10月份的50.8跌至11月份的50.3,这是3月份以来的最低读数。高于50的读数表示相关产业处于扩张之中。
2=中立

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

据当地媒体报道,这一犯罪团伙设在广西壮族自治区首府南宁,他们向腐肉中注射化学药品,使其增重50%,这样每吨腐肉便可获利16000元人民币(合1750英镑)。
silicon
16. Zapier

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

Mr. Anderson wanted an abundance and a variety of facial hair on the men, with no beard or mustache adorning each actor’s face in quite the same way. It’s a veritable hipster’s row of styles, from pencils to handlebars to a black-and-gray goatee worn by Jeff Goldblum.
After a run with One Direction, Harry Styles could have gone anywhere he wanted.

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

Copestake said fears over economic austerity and the stability of the euro had pushed the index of euro zone cities down in the past year while the inclusion of Caracas was due to artificially high exchange rate controls.
底特律三巨头:另两家底特律车企仍会遇到一些磕磕绊绊。通用还要继续应对“点火门”事件的余波,而福特将进入该公司有史以来最激进的产品发布期。
2012年,科学家开始认真寻找他的遗体。考古学家根据史书记载和地理线索,在一个市政停车场开始挖掘,并最终发现了遗骨。这里就是史书记载中埋葬查理三世的教堂的地点。

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

This year so far, Stephen Chow’s The Mermaid has made $526 million since its release in early February during Lunar New Year.

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

Ranking third on our Top-Grossing list is Steve Carell. Despicable Me 2 was a huge hit this year, bringing in $919 million at the box office. Overall, the franchise has earned $1.4 billion at the box office worldwide and a third movie, Minions, is on the way. Carell also appeared this year in the small indie The Way Way Back and The Incredible Burt Wonderstone. The latter failed to earn back its production budget at the box office but we’re only looking at ticket sales here — the film put another $22.5 million in Carell’s column for 2013.
The dollar value of exports from emerging market countries will rise next year for the first time since 2014, helped by higher commodity prices and modestly stronger demand, it is predicted.

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

米尔德里德的女儿7个月前遇害,但凶手仍然逍遥法外,主角一怒之下做出了一个大胆的决定:买下了小镇入口三张广告牌并在张贴图片中抨击颇有威望的警长威廉?威洛比。威廉的副手官迪克逊是一个幼稚的妈宝男,有暴力倾向。迪克逊卷入这件事后,米尔德里德和小镇执法系统之间的较量变得愈发激烈了。
8月首播的《秦时丽人明月心》全剧共48集,围绕着秦朝(公元前221-206年)时的争斗和爱情故事展开,剧情均为虚构。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

The potential impact of any surprise move in Fed policy was clear in the “taper tantrum” of 2013, when just the suggestion that the Fed might soon rein in its ultra-loose monetary policies was enough to provoke a wave of global panic.
继续开放

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
From the themed collection: 物流地产受追捧
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

Making Airbnb go away might not be so easy. A recent Quinnipiac poll found that 56 percent of the responders thought New Yorkers should be allowed to rent rooms out to strangers. “We don’t want to turn into hotels, but at the same time people want to rent out their apartments sometimes,” said Paul R. Gottsegen, the president of Halstead Management Company, which manages 250 residential properties in the city.
托米?韦素与格雷戈?泽斯特洛在旧金山一堂表演课上相识。格雷戈梦想着能在好莱坞崭露头角,搬来了旧金山,加入了托米的电影拍摄。托米自己出资,自导自演了《房间》(The Room)这部电影,后来该电影被批得体无完肤,很多人视其为邪典电影的经典。

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

SplashData的首席执行官摩根·斯兰说:“当你看到‘最差劲密码’榜单上出现‘adobe123’或者‘photoshop’,你就该意识到,在你正在使用的网站或应用上,不该用它本身的名字作为密码。”

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

May the season\'s joy fill you all the year round.
但经济学家总体上预计,一旦飓风造成的失真消失,前段时间的趋势就有望恢复并延续。接受《华尔街日报》最新月度调查的45位经济学家预计,到明年6月,失业率将降至7.8%,2013年年底将降至7.5%。部分经济学家说,就业增长可能会摆脱现在的缓慢速度而加快。信安环球投资有限公司(Principal Global Investors)经济学家鲍尔(Bob Baur)说,我觉得到时候企业将必须招人。[qh]
n. 扩大,膨胀,扩充
Kobe Bryant really hasn't changed that much since high school, even though it's been 16 years since he's walked the halls of Lower Merion High School.

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

停盘可能对深证综指起到了良好的作用,跌幅达8.22%的深证综指面临自2007年2月27日以来最大单日跌幅。此外根据FastFT的计算,自1996年12月16日中国股市实施10%的每日交易限制以来,今天这个缩短的交易日将列入深证综指第九大单日最大跌幅。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

泰勒·斯威夫特(Taylor Swift),《空白空间》(Blank Space), Big Machine
胡须的神奇之处
每次我跟人说起“未来”,我都被他们对“未来是可知”的这一想法吓到。我的印象就是,大部分人都想象未来像书本一样,有一个结局:已经写好了、也可以读取。你只要快速地窥一眼这本书的最后几页就能知道。他们很难接受这最后几页根本没有写完。未来还没有发生、也没有计划好——也无法预知,因为它们还根本不存在。

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

通用汽车(GM)咸鱼翻身不易,2010年举行首次公开募股一事就别惦记了。
狼和狗有何不同?

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

但经济学家总体上预计,一旦飓风造成的失真消失,前段时间的趋势就有望恢复并延续。接受《华尔街日报》最新月度调查的45位经济学家预计,到明年6月,失业率将降至7.8%,2013年年底将降至7.5%。部分经济学家说,就业增长可能会摆脱现在的缓慢速度而加快。信安环球投资有限公司(Principal Global Investors)经济学家鲍尔(Bob Baur)说,我觉得到时候企业将必须招人。[qh]
12306.cn, China's official website for purchasing railway tickets, has become the largest of this kind in the world, with combined sales reaching 3.5 billion in 2017.

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

锁定一个品牌,它擅长于制作你想要的类型的车,这样可以高效地购买并找到对你来说最好的车。2016美国新闻最佳汽车品牌奖从四个类别挑选了最佳的品牌:轿车、SUV、卡车和豪车。

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
From the themed collection: LED照明市场饱和 OLED开始发威
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

The house is on a slight hill above the street. Its entry is a large glassed porch with a brick floor and walls of windows facing the lake. The renovation preserved coffered ceilings and the abundant use of wood in the original part of the house. The floor plan is open, and nearly every room has views of the lake through picture windows.
The house is on a slight hill above the street. Its entry is a large glassed porch with a brick floor and walls of windows facing the lake. The renovation preserved coffered ceilings and the abundant use of wood in the original part of the house. The floor plan is open, and nearly every room has views of the lake through picture windows.
7.戛纳的“女性之年”并走运

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

6.Miniature Human Brains
对气候变化持怀疑态度的人长期以来认为,全球气温已在1998年左右停止变暖,那年是20世纪最热的一年,原因是异常强大的厄尔尼诺现象。华盛顿的一些政客用这种说法作为不对温室气体排放采取行动的理由。
事发时,Lecent正与其他年轻人一起在Finch大道,Martin Grove路附近的一家酒吧,她被一颗子弹击中,抢救无效死亡。
"That of course is in keeping with all of the developments that we have seen in China in recent years, including the current enormous emphasis on innovation as a major component in the transition of the Chinese economy from 'Made in China' to 'Created in China'," he said.

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

Washington's twin-obsessions in election year 2010 will be to create jobs and cut the deficit. Little will be accomplished on either count.
对于该行业规模有多大,众说纷纭,但高盛(Goldman Sachs)的数据表明,在2012至2014年期间,该行业的贷款规模从60亿元人民币增长至830亿元。

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

Adding pictures of family or objects that are close to you will remind you of what you’ve accomplished and why you work so hard. Keep them on your desk or on a shelf nearby to help you when you need encouragement and motivation. We love the Set of Ten Gold Frames, $28, at UrbanOutfitters.com.
Over the next few years, large residential buildings will have to comply with Local Law 87, which requires them to audit energy usage and keep systems running at peak efficiency. Residential buildings are the city’s largest source of greenhouse gas emissions, accounting for 37 percent of the total. “The one hot-button topic is energy. How do buildings become more energy efficient?” said Dan Wurtzel, the president of FirstService Residential New York, which manages more than 500 properties. “If a third of your operating budget is related to energy and you can now reduce that cost, you can take pressure off the need for a maintenance increase.”
n. 规章制度,草案,协议,外交礼仪

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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Frustrated, he invented something that would allow him take a picture of himself: He called it the "extender stick." Since the iPhone really hadn't been invented yet, a small camera was to be attached to one end of the stick. It also had a small mirror in its front so that users could see how they would look in the photograph. He patented the "extender stick" in 1983. The product was mass produced for sale but it was a commercial failure. The quality of the pictures was low. Besides, previous research showed that the women back then were embarrassed by the idea of taking pictures of themselves. The selfie stick was then reinvented by Wayne Fromm in the year 2000, three years before Hiroshi's patent expired. Fromm called his the "quik pod." He believes he is the inventor of today's selfie sticks and has even sued several other selfie stick producers. When asked about Hiroshi's selfie sticks, he said they were "prior art."
我是否在担忧未来?担忧某些并未发生的事情会导致压力和焦虑。专注于当下,了解到这就是目前所存在的一切。

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